Protein Details: Probable cyclic nucleotide-gated ion channel 14

Protein ID

ICDB_Pro_1631

Protein Name

Probable cyclic nucleotide-gated ion channel 14

Gene Name

CNGC14 At2g24610 F25P17.9

Organism

Arabidopsis thaliana (Mouse-ear cress)

Length

726 amino acids

AlphaFoldDB

AF-Q9SJA4-F1-model_v4.pdb

Function

Probable cyclic nucleotide-gated ion channel.

Sequence

MEFKRDNTVRFYGDEKQTIEVGEKRVPLFKSTTAPFMKQEVLPKKSKTRLKIPRFGRFKVFPENFEIERDKILDPGGDAVLQWNRVFLFWCLVALYVDPLFFFLSSVKRIGRSSCMTTDLKLGIVITFFRTLADLFYVLHIVIKFRTAYVSRTSRVFGRGELVKDPKLIARRYLRSDFIVDLIACLPLPQIVSWFILPSIRSSHSDHTTNALVLIVLVQYIPRLYLIFPLSAEIIKATGVVTTTAWAGAAYNLLQYMLASHILGSAWYLLSIERQATCWKAECHKESVPLQCVTDFFDCGTLHRDDRNNWQNTTVVFSNCDPSNNIQFTFGIFADALTKNVVSSPFLEKYLYCLWFGLQNLSSYGQNLSTSTSVLETMFAILVAIFGLVLFALLIGNMQTYLQSITVRLEEWRLKRRDTEEWMGHRLLPQNLRERVRRFVQYKWLATRGVDEETILHSLPADLRRDIQRHLCLDLVRRVPLFAQMDDQLLDAICERLASSLSTQGNYIVREGDPVTEMLFIIRGKLESSTTNGGRTGFFNSITLRPGDFCGEELLAWALLPKSTVNLPSSTRTVRALEEVEAFALQAGDLKFVANQFRRLHSKKLQHTFRYYSHQWRTWAACFVQVAWRRYKRKKLAKSLSLAESFSSYDEEEAVAVAATEEMSHEGEAQSGAKARHHTSNVKPHFAATILASRFAKNTRRTAHKLKDVEIPMLPKPDEPDFSVDD

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

BINDING 481..605; /ligand="a nucleoside 3,5-cyclic phosphate"; BINDING 552; /ligand="a nucleoside 3,5-cyclic phosphate"

Disease

Location

DOI ID

10.1038/45471; 10.1111/tpj.13415; 10.1104/pp.126.4.1646

RefSeq

NP_850056.1